Speaker Notes
- Walk through each row slowly — this table is the core content
- Use table controls: highlight men first, then women, then both
- Emphasize "Later initiation but faster progression" — this is counterintuitive
- Point out that severity at treatment entry is equivalent or higher
💡 Tip: Pause after "Age of Initiation" row — let audience notice women start LATER but progress FASTER
🎯 Key Point: The compression happens across ALL phases — this isn't about one vulnerable period
→ Transition: "Why does this happen? It's not behavioral — it's biological..."
Anticipated Questions
Q1:
"Are these differences statistically significant?"
Yes, consistently so across multiple large cohorts. The 3-5× faster progression to AUD is one of the most robust findings in addiction epidemiology. Confidence intervals are tight, effect sizes are large.
Easy
⏱ 1 min
Q2:
"What about transgender patients? Where do they fit?"
Excellent question with limited data. Hormone therapy likely shifts patterns toward affirmed gender, but research is sparse. My practice: assess individually, consider hormone status, avoid binary assumptions. This is an area needing more study.
Hard
⏱ 2 min