Speaker Notes
- Most critical safety slide—spend time here
- Emphasize "double danger": teratogenicity + contraceptive failure
- Ask audience about required contraception before revealing
⚠️ Watch for: Trainees thinking warning about pregnancy is sufficient
🎯 Key Point: LARC required—OCPs insufficient
Anticipated Questions
Q1
"What if she's on low-dose topiramate for migraine?"
CYP3A4 induction and teratogenicity exist at all AUD doses (>200mg). For migraine (50-100mg), interaction still exists. Always verify LARC regardless of indication.
Medium · 2 min