2024-2025 Evidence-Based Clinical Protocols
Distinguishes passive ideation from active intent with plan. Task-shifting to nursing staff improves ED throughput.
| Score | Risk | Action |
|---|---|---|
| 0 | Small | Standard care |
| 1-2 | Moderate | Preventive measures |
| >2 | High/Very High | Management plan |
Replaces "medical clearance" (implying no issues) with "medical stability for psychiatric admission."
If all negative: No further labs required.
| Status | Intervention | Medication |
|---|---|---|
| Cooperative | Oral (PO/ODT) | Risperidone 1-2mg, Olanzapine 5-10mg ODT |
| Uncooperative | IM | Droperidol 2.5-5mg (preferred), Olanzapine 5-10mg |
| Refractory | Dissociative | Ketamine 4-5mg/kg IM |
Superior to benzodiazepines. Loading dose 10mg/kg IV (IBW) over 30 minutes. Auto-tapers over days.
8-16mg SL initially; repeat at 60 minutes if symptoms persist. Rapid receptor saturation bridges to outpatient care.
| Feature | NMS | Serotonin Syndrome | Catatonia |
|---|---|---|---|
| Cause | D2 antagonists | Serotonergics | Psychiatric illness/BZD withdrawal |
| Onset | Slow (days-weeks) | Rapid (<24h) | Variable |
| Muscle | "Lead pipe" rigidity | Hyperreflexia, clonus | Waxy flexibility |
| Test | CK elevated | Hunter Criteria | Lorazepam challenge |
| Tx | Stop agent, dantrolene | Stop agent, cyproheptadine | Lorazepam, ECT |